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KMID : 0369319930130040521
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Allergy
1993 Volume.13 No. 4 p.521 ~ p.526
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A Case of occupational asthma caused by sea-squirt(styela plicata) in korea
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이명선
시해숙/박해심/김용재
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Abstract
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Hoya asthma is an occupational asthma among workers in oyster manufacturing factories in Japan, which usually develops after exposure to body fluids of sea-squirts. The prevalence of area in Japan is reported to be about seven percent in recent
years.
We experienced a case of occupational asthma who had worked in a mussel manufacturing factory for 5 years. He had suffered from cough, sputum, dyspnea, and rhinitis symptoms since one year ago. His symptoms were aggravated after exposure to
sea-squirts.
Total eosinophil count was 621/㎣ and total IgE-PRIST was 280 IU/ml. He showed positive responses on allergy skin prick test with common inhalant allergens(can fur 3×3/24×16, Chironomus plumosus 2×2/26×18, Tokunagayusurika akamusi
3×3/25×15(mm))
and with sea-squirt extracts9home-made extracts from Styela plicata 7×4/18×11, Hoya extracts of Torii Co. 2×2/4×3(mm)). IgE-RAST to d2, e1, I73 were class 0. The bronchoprovocation test with sea-squirt extracts showed dual asthmatic response.
PC20
methacholine levels before ant after the bronchoprovocation test with sea squirt extracts(day 1, day 5, day 8) were 14mg/ml, 0.62mg/ml, 2.3mg/ml, and 2.2mg/ml, respectively.
We recommended complete avoidence, and immunotherapy was tried with Hoya extracts from Torii Co. His symptoms were much improved with anti-asthmatic medications and immunotherapy.
In conclusion, an occupational asthma with exposure to sea-squirts(Styela plicata) was noted in a patient working at a mussel manufacturing factory in Korea.×
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